Dexamethasone [100 mL]

Dexamethasone is a synthetic analogue of prednisolone that has similar but more potent anti-inflammatory therapeutic action and diversified hormonal and metabolic effects. It is indicated for the treatment of primary bovine ketosis and as an anti-inflammatory agent in cattle and horses. As supportive therapy, it may be used in the management of various rheumatic, allergic, dermatologic, and other diseases known to be responsive to anti-inflammatory corticosteroids. It may be used intravenously as supportive therapy when an immediate hormonal response is required. Do not use in calves to be processed for veal.

PRECAUTIONS:

Animals receiving Dexamethasone should be under close observation. Because of the anti-inflammatory action of corticosteroids, signs of infection may be masked and it may be necessary to stop treatment until a further diagnosis is made. Overdosage of some glucocorticoids may result in sodium retention, fluid retention, potassium loss, and weight gain. Dexamethasone may be administered to animals with acute or chronic bacterial infections providing the infections are controlled with appropriate antibiotic or chemotherapeutic agents.
Doses greater than those recommended in horses may produce transient drowsiness or lethargy in some horses. The lethargy usually abates in 24 hours. Use of corticosteroids, depending on the dose, duration, and specified steroid, may result in inhibition of endogenous steroid production following drug withdrawal. In patients presently receiving or recently withdrawn from systemic corticosteroid treatments, therapy with a rapidly acting corticosteroid should be considered in unusually stressful situations.

WARNINGS:

Clinical and experimental data have demonstrated that corticosteroids administered orally or parenterally to animals may induce the first stage of parturition when administered during the last trimester of pregnancy and may precipitate premature parturition followed by dystocia, fetal death, retained placenta, and metritis. Additionally, corticosteroids administered to dogs, rabbits, and rodents during pregnancy have produced cleft palate. Other congenital anomalies including deformed forelegs, phocomelia, and anasarca have been reported in offspring of dogs which received corticosteroids during pregnancy. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.

Dexamethasone [100 mL] Highlights:

• SKU: 13091
• Manufacturer: Bimeda
• For animal use only
• Do not use in calves to be processed for veal.
• Store between 2degC and 30degC 36degF and 86degF
• Overdosage of some glucocorticoids may result in sodium retention
• Animals receiving Dexamethasone should be under close observation.
• Dexamethasone may be administered to animals with acute or chronic bacterial infections